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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac200a50010f9a48e8885a50f9ca710ed8b516f0b8cf1bfb5b549b79c047821' 
  AND token = 'drnxoAVmqcPxHC/EJ2Ml5975boJAnE6rnHkGIfpSV+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}