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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1234391f3d82f63027bb1916337ff925973e88e9a2ce339bdd9e980bf841fad' 
  AND token = '+BoFxVHFaP0h9jz3FEpb3TZaZFa9qPPBQm28/kV25qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}