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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e218688a18e603ed14f8977b1eea81fee2f44978dfab601f48d33c8a4ca0d21' 
  AND token = 'o9Dz7/tHCxhCD1O7VLrT2Nu63c4r/c9le9y93MSC7z0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}