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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14aade21c926500d563fdeb657e0edcc0d7c6aa6b56874bdc753b6f0b0945ec' 
  AND token = 'kuaKOmw1L2igo1SpBZACkh+fv8pSxeLO3ytpA6ommLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}