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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1fed0844b09a924e2c86f755c0ee813fc997f9e3b4e245c4d3dc49e56c3dad' 
  AND token = 'cy607F+vk42O/j1h2H90F1IwHiMArVVKcgXQem08hW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}