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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c742135a6c824129771e27737d19011a25adb8b3170f0346fba27d4a4f862cd6' 
  AND token = 'eUQ90SzgVhlSFZQ5ayFwC3SS+LaiWHJdkTt/if/Qx70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}