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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a22ca1ea2e1da5ca1b262768ebb75b5f9ad19e85e9fda04f7d89971423d9434' 
  AND token = 'Zf1VFx89RbPKNZqaPgxTCMcvs27Yvg9JQCyRg52ll+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}