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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09f57033a834c7a0c323201b025067ccc4538610addd14708f0f930154ec8d17' 
  AND token = 'jMB3LVUUzUbX/M/8QXlO6aIBl1GQYv9pgciS61OQ2TA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}