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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d1d2be1bd8080262846a5a0d3980b89990ac3a9b45a599f992d879e32c89562' 
  AND token = 'xti6n7aOTanHbIrGM73+V7Xkna7EKk0PbZNAo+gT95k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}