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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850c17f31b79358d268f43c1dbac47f58e1c8d9c0ff847625a5eb8c929d458da' 
  AND token = '5+yn/0EA8gzilwFPDvLoCsddgSwfBsOyGx8ObbUnm8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}