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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544025b23f6f82226b2e25dfc067cef82e84ba788d066d0f606b1c98aab0811d' 
  AND token = 'YIdwDHRSV2kM2iAxF4ytLC9kYYhuru9WeD9FUXMn4cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}