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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede28d4712b5531428324b5fab354e8a3d731f433f18853070d7af098c18d1f2' 
  AND token = 'd1S5L16ssVk4NOwG5hj6waRWnCwY5wRvjDaQLk3HlFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}