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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4df294cf06c9937bfb5aa1127571e4cbb95111e5f6e0a1028019faf914a4cf2c' 
  AND token = 'tg3y3Rn/2RyS15R0o+ItuMPV7YcQR0bvh2i8I4d1lhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}