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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b29e59e85f85588d2dd4fa0c4e360b3fd952eaad1bb9df72e2f5617c79f4f6f' 
  AND token = 'IwHrklEGXn9TdVuF9Pnz6A2gJFvvBvZMcElDBHrS5o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}