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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81c0ff99f0d620baa2d3a6180bc4ce6e0a3c67c84ee36e2e9c4563599d3c553' 
  AND token = 'lMb978DVSjdUKOJ4ieHDxcwcZdLmC1EzOvLs4+8JTEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}