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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41672b0ebb379ebaf19193fd384ab1a2c5112de025588c30a860cac9583f4592' 
  AND token = '775rW2t0b2eEbkdMkUI8JhsHhLBnA6ao9C3zEY4SgiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}