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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4fbbe103816a70183a3d4d8183e224790c56e4f1d1b963eab0012a420d46b7' 
  AND token = 'JSh97q0iCpKLdT4sf8KtdI+uxOzqneAlAMhMDiH18ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}