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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66818b3e1d77f660a9f133b6e3f03f3108fb978f74eade0206d4e38e2ee12ebb' 
  AND token = 'Wr4MUtA6WfXHN8aLgeDrOIGlxTT90hrLuysvOAe/1yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}