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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f24478a88296dc1e60217a4d1fcf5ad3a890e1cc981921bb1dc29d5b11266599' 
  AND token = 'N2OudT/Gi3b9B+b7LNOFYvEoRm/71wGq1eqOgttuh9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}