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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d4c431ca2f61a192198f2de5cb009dc21c07ec8ed69eeec8acc3b7760debca' 
  AND token = '7wQr55OyVMEluokExxLYZT0bIEBqY4p+6j8elRA50io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}