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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f934cb75c661932d5a536383f168a42c8263c4549caacf0d6f8537731a862e64' 
  AND token = 'SYpvnmsq04NPxCk/p+u/l9ZVERrD5u1PNlIQ6ti3OLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}