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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06da9e21f2c63101721d91ce5524808b73b203f0359d9b428d5e21bd9bfebc9a' 
  AND token = 'CIs6s8GEyYYsXhtCiNoZO8n5KTvUXtFFCpJzysKC4iU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}