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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e154a1fd09649cc5660915da757cb41d5263da7088f6d12061d4c45030de6dd' 
  AND token = '+MvJPtHHDMWQaJ1gjebzprmbQ79MGlAgRhVnDWcd6PQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}