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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed186879a5f9bed6316711cf6cbed07b2d708956085260896d9627add15443f1' 
  AND token = 'ReAJOpisvC0INU+ciKrKIvN6jvDSLLLQ1NgSVq0ufoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}