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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f9662da281fe7c4e596a28c830fa4cb5726f7859872aab87912243f2b72889' 
  AND token = 'U33Vy/YlD1ajAQ7e1D0rQK8/0ZJi+P/f0XgMfl3WhN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}