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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f5b5ed971bf1cb57cc8fc6bee419f63dcb6217418d4a68b17403cc655be2925' 
  AND token = 'ZWcSjpwki4NqF4J3d4SF7RHpGp2aYh0Fqgf7OE7tyhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}