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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b873b10300de8bde8423147932394a21da6643c431436c45cfe7f8294395dc' 
  AND token = '+T5k+Ky2riSux4M27qVoekLBQQZv8cSv7rJnadsmFPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}