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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453d70375974a4ee02fef9f01ea3f1494e749fba6dad9d803b83e37c40c6cd35' 
  AND token = 'DdhQkSQLSKPLaajOafGKKzQuVXchdCJehEHnwvZi9nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}