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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7345d1f1f586ecc87bf6913e9382da4b33fdb47ea63f9a215b277b1ced287f96' 
  AND token = 'PEco4b2qC1vKoYe08O+BypbB3bfe6Ctqk2ve8+t7mI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}