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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4021d669bb5a77883e0744220af6d75da681822f2a8de7e34989b7f4978401a4' 
  AND token = 'o74+5CwiFpbCo5AI5Tko5b+L9/kr/NESyGAA4/15nXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}