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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c321bcd0c1279796667cf1b87d73e3a181c376e05fa0bc0a45c32704509116d' 
  AND token = 'hxuCi1YHE9fXWCBDRul7JgW9YnwP69XYsHWP+w3cuqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}