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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '075b4c476fa2129325bd11b169b5b2157bfbaa08b5851223ffcfa5edcb076c40' 
  AND token = 'H4gTIYI3d/3NFdpMuP4vtbjF+XuAGWx9fkRZ9NmWGAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}