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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16c8b4096ca7cfed45c4acf71f8b272de166ba5cbced631bfcfe6178c91d40f' 
  AND token = 'g9Dj51kptwJoMqCg8RP76nmhfYIx4uf1JJ9bG8p84ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}