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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a53e35e58d367b4b95e8b886ef2359db74353368da8707345d83d2a9edb4f9f1' 
  AND token = '9SRMrKx8llXU9UoL6SFyrSy63UO4ihRcLX4GDdx6REs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}