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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2727d56e384f890578575b9b0a522e6d893e62e653a4316b28deb36bdcfc22d6' 
  AND token = 'iPPmoxS4H8aRmL1u9/71HsexAUCw3E9k1+iEHh3tPjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}