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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cacf9e29acf1c310ab3d199331789a395783a786302fbf1408c8421b792851' 
  AND token = 'amR03Wxp2trqIAkPHWnDqZvKjOIGmFZ6p33rwPR4xS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}