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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '264cb054ac7a8c62242ad82ce1c6ee2e225ef966467e2b76c113474342e8771f' 
  AND token = 'QGREBmPfitgkOIgwDHo5B8AdzLL+AHypdsgWN28a5bI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}