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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9bc8d9a817f8726b32af6328d7ede1352a3e642b9eda0a252cde5635c180dd' 
  AND token = 'oy921r4KHPTeLYD6ZcpwkXLcTP+y6Wb7f8Ent6vFWm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}