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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6c292dee7ed733e44540267b74bd5554449bc1f690cf9a2d5f2b648bb03d8e' 
  AND token = 'bwJX8NrZ6L7ACSV2//o9X3ZAvIk2QIvJildfsN0e/cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}