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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d91bff2b7608025cbbb73d864b5cd3c98572fc64aab4a2538b90a351c753956' 
  AND token = 'ONO+ML/D9IjjatJiOC5wg14L2y6C73/+SI2bNKD0Zr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}