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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaaf900f6768f191adc1dc7377f497720022b08be6bc85a330b91d3c209deb76' 
  AND token = 'jC9Kv1Tmm8CnMo8q/WeHNPEVc306aDr0cUBXNPe/KiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}