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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c4335fe2db7163e021d1c90c8ccf962a8d8ff2c1ff1fac6802662ccb894024' 
  AND token = 'ua2PwK9zeYkyX6zzF740zrauo+oZjf/qCrFQOhY0geg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}