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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c859e287fac07a461fc535acbc4626c4be8d86be8aaf14b6d3cf6493b85970' 
  AND token = 'ghezcZPpD975XLSFNg5lg0dK7djE4smBAGKMT9WN5oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}