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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c037d1fca4d758e3262279e418a398610ccf8273c0627e1de59f0b7087cd9be2' 
  AND token = 'Q5U976szZM+SHQ5FtBD+UPpl72SwQBFukKRiSsfGQX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}