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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42ff454652f8bfbca3e75919878a386b380e60acb11418809b4b96f4e9ef3da' 
  AND token = 'TpK7nXAGY/7pUB5q3tau4LvP/3nuXbCxa0HeiW8Grxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}