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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50b0462a4c8999adc91e915be2f27bb5a20c66bf18b7830746ef30a5dd270f4' 
  AND token = 'OJTP9/Jjf8mFSA7k9SUzj3jODj0Y4bxfU3Z4UzIXOBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}