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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b531f6a79818e8b1375af585605895b24d3fc1053de20c0521a5bd2d5c274adf' 
  AND token = '/GgxLQ4Exu9Dybn2iqdaiXHV02F5O7ppc1n/bJMC4pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}