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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa4bc63bffde60a990fe15eea6950f289a1efaf7aa97187824f1c357fa27480' 
  AND token = 's7vMEHBT1GaNZdyaIkG6ghyMcWzISgmMzRTyXpyCWxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}