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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '479535f80a34d4ff569e91fe502bee634fcb1f2ffb7b20d7fc00c39665af3465' 
  AND token = 'q0QCFVBqw5Yb1PxSLOo466YcrsImjqqP0eXCLvKr1fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}