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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538b0dd2a712e12261fb82c0479563efe5f1188204003bd953444d69404cff79' 
  AND token = '4QjyHSz+CzQ5MbXNjOdIy+NqNH2AQHOt1WvgYxnZ0Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}